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Fatigue means low energy and is a common symptom in PD. Fatigue often overlaps with sleepiness and/or depression. Because medication treatment options for fatigue may be of limited benefit, treatment of any overlapping sleepiness or depression is paramount. Lifestyle changes are also important, including budgeting energy for your most important activities, exercising regularly, eating well, drinking lots of water, getting enough sleep, and taking breaks when needed. Spending time with other people helps some people feel more engaged and energetic. Medication can have some benefits for fatigue. Possible side effects include headaches, dizziness, anxiety, nervousness, and insomnia.

Disclaimer: The information provided on this Parkinson Association of Alabama Resource Center is for awareness and educational purposes only about Parkinson's medication. The PAA does not endorse any specific brand or type of medication. All discussions about medication should be between you, your care partner, and your medical teams.


Davis Phinney Foundation. Parkinson's Treatments and Therapies. Chapter 7 - Medication. Page 115. Every Victory Counts. "Manual." Sixth Edition, 2021.

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